Zestoretic (Lisinopril/HCTZ) Indication

Zestoretic and Lisinopril/ HCTZ (generic for Zestoretic) is used to treat patients with congestive heart failure, and high blood pressure (hypertension), and to improve survival after a patient has had a heart attack.

Storage

This medication should be stored at room temperature. Keep the medication away from heat and moisture.

Precautions

Inform your doctor about the following before taking Zestoretic (Lisinopril/HCTZ):

1. If you are pregnant, plan to become pregnant, or breastfeeding
2. If you have liver or kidney disease
3. If you have diabetes
4. If you have a heart disease or congestive heart failure
5. If you have a connective tissue disease (i.e., Rheumatoid arthritis, Marfan syndrome, Sjogren’s syndrome, lupus, or scleroderma).

Warnings

1. When taking Zestoretic (Lisinopril/HCTZ), avoid alcohol because it can lower blood pressure and increase the side effects of Zestoretic (Lisinopril/HCTZ).
2. Also, when taking Zestoretic (Lisinopril/HCTZ), avoid potassium supplements or salt substitutes unless your doctor has instructed you to.
3. While on this medication you may experience vomiting, heavy sweating, and diarrhea. These are common symptoms and will cause you to become dehydrated leading to very low blood pressure, kidney failure, or electrolyte disorders.
4. Make sure you drink plenty of water every day while on this medication.

Patient Family Information

• Read the directions on the prescription label.
• Do not take larger doses than prescribed by your doctor.
• Do not take this medication longer than recommended by your doctor.
• Take this medication as directed by your doctor.
• Patients taking Zestoretic (Lisinopril/HCTZ) may have their dosage changed by their doctors occasionally to attain the best results.
• Take Zestoretic (Lisinopril/HCTZ) with a full glass of water and with or without food.
• Regular doctor appointments for blood pressure tests and kidney and liver function tests will be required to ensure the medication is helping the condition.
• There are no symptoms for high blood pressure, continue taking this medication even if you feel fine.
• If you need surgery of any type, let your surgeon know ahead of time because you will need to stop taking the medication for a short period of time.

Contraindication

• Do not use Zestoretic (Lisinopril/HCTZ) if you are pregnant because it can cause birth defects to an unborn baby.
• During treatment, use an effective form of birth control.
• If you become pregnant while taking Zestoretic (Lisinopril/HCTZ) stop taking the medication and let your doctor know immediately.

Severe Side Effects of Zestoretic (Lisinopril/HCTZ)

Severe side effects include:

• Fever, chills, body aches, flu symptoms
• Chest pain
• Feeling light-headed, fainting
• Swelling, rapid weight gain
• Urinating more or less than usual, or not at all
• Tired feeling
• Muscle weakness
• Pounding or uneven heartbeats

Common Side Effects of Zestoretic (Lisinopril/HCTZ)

Common side effects include:

• Vomiting
• Diarrhea
• Nausea
• Upset stomach
• Cough
• Mild skin itching or rash
• Dizziness, drowsiness, headache
• Depressed mood

Other Drugs

Nexletol | Teveten Plus | Nitrostat Sublingual

References

2022. Zestoretic – Uses, Side Effects, and More. WebMD. https://www.webmd.com/drugs/2/drug-5591/zestoretic-oral/details