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LIALDA (MESALAMINE) INDICATIONS

Lialda is an extended-release tablet and an oral prescription approved for patients suffering from inflammatory bowel disease. It is indicated to induce remission in patients with active, mild to moderate ulcerative colitis.

It belongs to a class of medications known as aminosalicylates. Its generic name is mesalamine (also known as 5-aminosalicylic acid or 5-ASA).

The digestive tract helps food , pass through the gastrointestinal tract and out of the body. The body absorbs the nutrients you ingest, and the rest is excreted through feces or urine.

In patients with ulcerative colitis, the lining of the colon becomes inflamed, swollen, and irritated. It is a chronic inflammation that can lead to the development of ulcers in the colon, causing symptoms such as frequent bowel movements, bloody stools, fatigue, anemia, nausea, and weight loss.

When Lialda is administered correctly and reaches the bowel, it has an anti-inflammatory effect. Its mechanism of action works by blocking cyclooxygenase and inhibiting the production of prostaglandins that cause inflammation.

As a result, Lialda helps relieve stomach pain or discomfort and reduces loose bowel movements and other symptoms associated with ulcerative colitis.

LIALDA (MESALAMINE) USES AND DOSAGE

Lialda (mesalamine) is used for the treatment of mild to moderate ulcerative colitis by causing and maintaining remission.

Individuals can participate in social gatherings, family gatherings, and work-related activities by using Lialda without worrying too much about an embarrassing incident that can be caused by ulcerative colitis.

The dosage and frequency of mesalamine differ from one person to another. It will depend on the severity of your existing health problem, other medications you are on, and tolerance to the regimen. If you are uncertain how to use Lialda, talk to your doctor or pharmacist for clarification.

The following are the directions for administering Lialda (Mesalamine):

  • Administer Lialda orally two to four times a day (six hours apart) or as prescribed by your doctor.
  • Take Lialda with food or after meals or as recommended.
  • Make sure not to chew, crush, or cut the tablet because doing so will cause the medication to release its components before it reaches the colon.
  • Treatment duration can last up to eight weeks.

Be sure not to stop using Lialda unless instructed by your healthcare provider. Your doctor will be the one to determine how long you should use this medicine, depending on how your body responds to the therapy.

SIDE EFFECTS LIALDA (MESALAMINE)

Lialda (mesalamine) tablets may have unwanted side effects like similar medicines that may resolve over time when your body has adjusted to them. Most individuals may experience mild side effects. However, stop taking Lialda and contact your doctor right away if it becomes persistent and bothersome.

Common side effects that may occur when taking Lialda may include:

  • Headache
  • Flatulence
  • Increased alanine aminotransferase
  • Hair loss (alopecia)
  • Itchiness (pruritus)

SERIOUS SIDE EFFECTS

  • Fast heart rate (tachycardia)
  • High or low blood pressure
  • Acne
  • Hard, extremely itchy bumps (prurigo)
  • Rash
  • Hives
  • Abdominal distension
  • Diarrhea
  • Pancreatitis
  • Rectal polyp
  • Vomiting
  • Low platelet count
  • Elevated total bilirubin
  • Joint pain (arthralgia)
  • Back pain
  • Drowsiness Tremor
  • Pain of nose or throat
  • Face edema
  • Weakness
  • Fatigue
  • Fever
  • Myocarditis (inflammation of the heart muscle)
  • Pericarditis (inflammation of the pericardium)

ALLERGIC REACTIONS

  • Skin rash
  • Hives
  • Skin blisters or peeling
  • Swelling (face/tongue/throat)
  • Trouble breathing or swallowing

Remember, this is not a complete list of all potential health risks associated with Lialda. Call your healthcare provider for additional information about other side effects not listed above associated with mesalamine.

LIALDA (MESALAMINE) CAUTIONS

Healthcare providers and patients are cautioned about the risks and benefits of taking Lialda gastric medication, especially in individuals with pyloric stenosis, as this can cause prolonged gastric retention of Lialda, delaying its release in the colon.

In addition, patients should be advised that Lialda is associated with acute intolerance syndrome that may warrant discontinuation of the therapy. Make sure to watch out for signs and symptoms, such as acute abdominal pain, bloody diarrhea, fever, headache, and rash.

Lialda has been linked to mesalamine-induced cardiac hypersensitivity reactions (myocarditis or pericarditis). It is best to use precautions when giving this medication to individuals that have a disease that puts them at risk for myocarditis or pericarditis.

Before administering Lialda gastric medication, make sure to fully disclose your health history to your doctor, especially if you have kidney problems, are pregnant, or are a lactating woman.

Do not take Lialda if you are allergic to mesalazine or other any of its inactive ingredients. Get medical help as soon as possible when allergic reactions develop when using this gastric medication.

Inform your doctor about all the medicines you are taking to prevent unwanted drug interactions, especially if you are on nephrotoxic agents such as:

  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Azathioprine
  • 6-mercaptopurine

Keep mesalamine tablets out of reach of the children and store them safely to preserve their effectiveness.

LIALDA (MESALAMINE) FORM AND STRENGTH

Lialda oral gastric medication is available in delayed-release or extended-release formulation with the following strengths:

  • Lialda
    • 2 g extended-release tablet
  • Generic Lialda (Mesalamine)
    • 1200 mg enteric coated delayed-release tablet

FAQ

What is Lialda (mesalamine) used for

Lialda is used for the treatment of an intestinal condition known as ulcerative colitis. It helps relieve symptoms associated with it, such as frequent bowel movements, bloody stools, fatigue, anemia, nausea, and weight loss.

What are the common side effects of taking Lialda (mesalamine)?

The following are the common side effects that may occur when taking Lialda:

  • Headache
  • Flatulence
  • Increased alanine aminotransferase
  • Hair loss (alopecia)
  • Itchiness (pruritus)

How long should I take Lialda (mesalamine)?

Your doctor will be the one to decide how long you are going to use Lialda in treating ulcerative colitis. However, clinical trials show that this treatment duration can be up to eight weeks.

When is the best time to take Lialda (mesalamine)?

It is best to administer Lialda two to four times a day, six hours apart. It is taken with food or after meals to avoid stomach upset.

Additional information

Scientific Name:

Mesalamine

Formulation:

Delayed Release Tablet, ER Tablet

Strength(s):

1.2g, 1200mg

Quantities Available:

60, 90, 120, 180, 360

MedicationsCanada.com receives the above information for Lialda (Mesalamine) from third parties. We provide this information for general informational purposes only, and it is not intended to replace the advice of a physician. Any medical concerns should always be discussed with your doctor or a qualified health care professional.