DALIRESP (ROFLUMILAST) INDICATIONS

Daliresp is an oral prescription indicated to treat patients with severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. This medication lessens the frequency of developing flare-ups or worsening of COPD symptoms.

Its generic name is roflumilast, which belongs to a class of medications known as selective phosphodiesterase-4 (PDE4) inhibitors.

COPD is a lung condition that makes it difficult for the lungs to expel air, which causes difficulty in breathing.

When Daliresp is taken correctly and absorbed into the bloodstream, it works by inhibiting PDE4, an enzyme responsible for regulating inflammation in the body related to COPD. This activity leads to the accumulation of intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3′,5′-adenosine monophosphate (cyclic AMP).

Increased cyclic AMP levels prevent mast cells from releasing inflammatory mediators that can cause inflammation, thereby causing the narrowing of lung airways. As a result, the number of flare-ups or the worsening of COPD symptoms is reduced.

Bear in mind that Daliresp is not a bronchodilator. In addition, it is not approved to use in patients with acute bronchospasm.

DALIRESP (ROFLUMILAST) USES AND DOSAGE

Indication of Daliresp (roflumilast):

• Reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of flare-ups.

Dosage of Daliresp (roflumilast):

Most patients who have COPD require varying amounts of roflumilast depending on their needs. The frequency and dosage are usually based on the severity of the client’s current health condition, other coexisting medical problems, age, and tolerance to the medicine.

The recommended dosage is to administer one tablet of 500 mcg once a day or as prescribed.

The following are the directions for administering Daliresp (roflumilast):

• When using Daliresp film-coated tablet, make sure to read all prescription information and follow all the directions thoroughly. If you are uncertain about how to use this oral medication, talk to your doctor or pharmacist for clarification.
• Administer Daliresp orally once a day or as prescribed
• Take Daliresp pills with or without regard to food

SIDE EFFECTS OF DALIRESP (ROFLUMILAST)

Roflumilast may have unwanted side effects similar to other medications that may resolve over time when your body has adjusted to the medicine.

Common side effects that can occur when taking roflumilast medicine include:

• Diarrhea
• Weight loss
• Nausea
• Headache
• Back pain
• Flu-like symptoms
• Trouble sleeping
• Dizziness
• Decreased appetite

SERIOUS SIDE EFFECTS

• Mental health problems
  • Suicidal thoughts
  • Attempts to commit suicide
  • Trouble sleeping
  • New or worsening anxiety
  • New or worsening depression
  • Impulsivity
  • Other unusual changes in behavior or mood
• Weight loss

Note that this list does not include all the drug information and health implications related to Daliresp (roflumilast). Call and ask your healthcare provider for additional information if you develop other side effects not listed above while taking this medication.

DALIRESP (ROFLUMILAST) CAUTIONS

Be very cautious about the risks associated with Daliresp, as this medication can cause mental problems, such as suicidal thoughts and behaviors. Watch out for sudden changes in mood or behavior and immediately call for emergency help if any of these occur.

Before using Daliresp medication, make sure to fully disclose your health history to your doctor, especially if you have the following medical conditions:

• History of mental health conditions (e.g., depression or suicidal behavior)
• Liver problems
• Other medical conditions
• Pregnant or planning to get pregnant
• Breastfeeding or planning to breastfeed

Do not take Daliresp if you are allergic to roflumilast and its inactive components. Seek medical attention as soon as an allergic reaction occurs. In addition, do not administer this oral pill if you have liver disease, as this can aggravate your health problem.

Taking Daliresp medication may cause weight loss. Make sure to monitor weight regularly and report significant and unexplained weight loss immediately.

Bear in mind that there are not enough studies on whether this medication is safe for pregnant and nursing mothers. Make sure to consult your doctor before using any medicine to prevent harming yourself and your baby.

Tell your doctor about all the medications you are taking when using roflumilast to prevent unwanted drug interaction, as it may affect the way other medicines work.

Keep Daliresp tablets out of reach of the children. Store these pills safely to preserve their effectiveness.

DALIRESP (ROFLUMILAST) FORM AND STRENGTH

Daliresp oral PDE-4 inhibitor medication is available in tablet formulation with the following strengths

• Daliresp
• • 500 mcg film-coated tablet

FAQ

Is Daliresp (roflumilast) a steroid?

No, Daliresp is not a steroid medication. It belongs to a different class of medicines called phosphodiesterase 4 (PDE-4) inhibitors that help reduce the frequency, risk of having flare-ups, or worsening of symptoms associated with COPD.

What are the side effects of Daliresp (roflumilast)?

Common side effects that can occur when taking Daliresp oral PDE-4 medication may include:

• Diarrhea
• Weight loss
• Nausea
• Headache
• Back pain
• Flu-like symptoms
• Trouble sleeping
• Dizziness
• Decreased appetite

What is the best time to take Daliresp (roflumilast)?

Generally, Daliresp is given once daily, preferably at the same time every day, with or without regard to food. However, make sure to follow your doctor’s order when taking this medicine.

How much does Daliresp (roflumilast) cost?

Many online and local pharmacies dispense Daliresp oral PDE-4 inhibitor medication. With the use of modern technology, you may conveniently look for apothecaries where you can quickly buy this medicine.

The price of this oral prescription is relatively affordable. Usually, the cost of Daliresp depends on the quantity and strength you purchase. Check the pricing information regarding this medication at the top of this description.

Can Daliresp (roflumilast) cause weight changes?

Yes. Weight loss is a common adverse reaction of Daliresp medication. It is recommended to monitor weight regularly while taking this regimen and immediately report unexplained and significant weight loss to your doctor.